Clinical Trials and Translational Studies

  1. UCSD IRB#140072—Metabolomic Studies of Complex Chronic Disease
    1. Ongoing or Completed
      1. Autism Spectrum Disorder (ASD)
      2. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
        1. CFS1 (2015)
        2. CFS2 (2017)
      3. Major Depressive Disorder (MDD)
      4. Post-Traumatic Stress Disorder (PTSD)
      5. Traumatic Brain Injury (TBI)
      6. Metabolomics of routine vaccinations in children
      7. Primary Sclerosing Cholangitis (PSC)
      8. Exercise and Aging
      9. Primary Mitochondrial Disease
    2.  Planned
      1. Gulf War Illness (GWI)
      2. Post-Treatment Lyme Disease (PTLD)
      3. Systemic Lupus Erythematosis (SLE)
      4. Amyotrophic Lateral Sclerosis (ALS)
      5. Pharmacometabolomics of Commonly Prescribed Medications
  2. UCSD IRB#150134—The Suramin Autism Treatment 1 (SAT1) Trial—Completed.
  3. UCSD IRB#172040—Suramin Pharmacokinetics in ASD
  4. UCSD IRB#171940—Can the Risk of a Future Diagnosis of Autism be Measured by a Metabolomic Analysis of Universal Newborn Screening?
  5. UCSD IRB#170199—Pilot Study of Suramin Treatment in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
  6. Basic Research Studies
    1. The Dauer Response and Recovery in C. elegans
    2. The Systemic Hyperpurinergia Response in Mice
      1. With breathomics analysis
    3. Broad-spectrum Toxicomics methods
    4. Dried Blood Spot (DBS) Metabolomics methods